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bp0008rdr23 | Corpus Luteum | REDR2014

Corpus luteum development and angiogenesis

Robinson Robert S , Woad Katie J , Hunter Morag G , Sinclair Kevin D , Laird Mhairi , Joseph Chitra , Hammond Amanda J , Mann George E

Summary. Development of the corpus luteum (CL) is vital for the early increase in postovulatory progesterone that drives embryo development and the successful establishment of pregnancy. Following ovulation, rapid and dramatic cellular reorganisation and intense angiogenesis are required to support the timely transition to progesterone secretion. In addition to inherent physiological challenges, this process is sensitive to any imbalance in metabolism or healt...